The effect of ginger on hormones secreted from pituitary and ovarian tissue Female rat

Abstract

Introduction: Ginger is used as a food, spice, herbal supplement for its antioxidant, anti-inflammatory and medicinal activities. The part of ginger that is used is its rhizome, which is the underground stem and is used as a spice as well as a medicine. This plant regulates the production of gonadotropin. Disorders of the female reproductive system such as hormonal and ovarian tissue disorders and how to prevent and treat them are one of the most important topics that researchers are now focusing on. The purpose of this study is to investigate the effect of ginger on hormones secreted from the pituitary gland and ovaries in female rats. Materials & Methods: 32 adults female Wistar rats weighing approximately 250 grams and 12 weeks old were randomly divided into 4 groups, the control group (without any treatment) and three groups treated with doses of 120-60 and 180 mg per kilogram of body weight per day. Dry ginger was added to their diet for 30 days. At the end, by taking blood from the heart, the levels of FSH, LH, estrogen, progesterone and testosterone in the serum were measured, and then the data were analyzed using spss21 software and through one-way ANOVA tests and Duncan's post hoc test. Results: The results of this research showed a significant increase in the amount of LH in the group treated with a dose of 180 mg per kilogram of weight compared to the control group and the amount of estrogen in the group treated with a dose of 120 and 180 mg per kilogram of weight compared to the control group. gave Also, no significant differences were observed in serum FSH and testosterone levels. Conclusion: The research results show that ginger can increase LH, estrogen and progesterone hormones in rats.